I wanna hold your hand!
Hand-holding affects the human brain by making it more capable to handling stress. This is my interpretation of the 5 October 2006 NY Times piece "A Show of Hands."
James Coan, an assistant professor of psychology and the neuroscience graduate program at the University of Virginia, has studied the impact of human touch, particularly how it affects the neural response to threatening situations, and said the results of a recent study were more dramatic than he expected.
“We found that holding the hand of really anyone, it made your brain work a little less hard in coping,” Dr. Coan said, adding that any sort of hand-holding relaxes the body.

The study, which will be published this year in the journal Psychological Science, involved 16 couples who were rated happily married based on the answers in a detailed questionnaire. The wives were put inside an M.R.I. machine and were told they were to receive mild electric shocks to an ankle. Brain images showed that regions of the women’s brains that had been activated in anticipation of pain and that were associated with negative emotions decreased when their husbands reached into the machine.
“With spouse hand-holding you also stop looking for other signs of danger and you start feeling more secure,” said Dr. Coan, who led the study. “If you’re in a really strong relationship, you may be protected against pain and stress hormones that may have a damaging effect on your immune system.”
Perhaps it is why so many people crave it.
I wonder if this has anything to do with Oxytocin, the neurotransmitter that's been linked to maternal bonding and is considered an anti-stress hormone as well.

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